Understanding Letrozole: What Is It?

Letrozole is a medication primarily used in the treatment of certain types of breast cancer. It belongs to a class of drugs known as aromatase inhibitors, which work by decreasing the amount of estrogen produced in the body.

How Does Letrozole Work?

In women with hormone receptor-positive breast cancer, estrogen can promote the growth of cancer cells. Letrozole inhibits the aromatase enzyme, which is responsible for converting androgens into estrogens in postmenopausal women. By lowering estrogen levels, letrozole effectively slows or stops the growth of these hormone-sensitive tumors.

Indications for Use

Letrozole is most commonly prescribed for:

• Postmenopausal women with hormone receptor-positive breast cancer.
• Adjuvant treatment after surgery to reduce the risk of recurrence.
• Treatment of advanced breast cancer that has progressed following other hormonal therapies.

Dosage and Administration

The typical dosage of letrozole is 2.5 mg taken once daily. It can be administered with or without food. It’s essential for patients to adhere to their prescribed dosage and schedule to achieve optimal results.

Potential Side Effects

letrozole may cause side effects. Common side effects include:

• Hot flashes
• Joint pain
• Fatigue
• Nausea

Some patients may also experience bone density loss, increasing the risk of fractures. Letrozol-ratiopharm 2,5 mg Regular monitoring and consultations with healthcare providers are crucial during treatment.

Conclusion

In summary, letrozole plays a significant role in managing hormone receptor-positive breast cancer in postmenopausal women. Its ability to lower estrogen levels makes it an effective treatment option, but awareness of potential side effects and ongoing medical supervision is essential for its successful use.